A man and woman have been rushed to hospital following a serious crash on the Kwinana Freeway in Karnup.
Emergency services were called to the single vehicle crash near Paganoni Road around 11.15pm on Tuesday.
The RAC rescue helicopter airlifted the driver, a 45-year-old man, to Royal Perth Hospital with serious injuries.
A 24-year-old female passenger was also taken to Royal Perth Hospital by ambulance with serious injuries.
Police say inquiries are continuing into the crash.
The Kwinana Freeway was closed in both directions for over five hours causing major delays for motorists on Wednesday morning.
Man arrested after attacking child, elderly traffic warden in Baldivis
Mandurah land owners reminded to prepare properties ahead of bushfire season
Ten high-rise apartment towers set for Rockingham
Safety Bay man accused of child sex offences back behind bars after allegedly breaching bail conditions
Daytime case management services now on offer to Rockingham homeless
Police hunt group of 13 masked teens who stormed Baldivis bottle shop
Missing 11yo girl last seen in Dudley Park
Crowds flock to meet One Nation leader Pauline Hanson during Secret Harbour visit
Sales manager allegedly steals $120k from Rockingham car dealership